Circulating Calreticulin Is Increased in Myelofibrosis: Correlation with Interleukin-6 Plasma Levels, Bone Marrow Fibrosis, and Splenomegaly

Figure 2

Correlation between CRT plasma levels and BM fibrosis, splenomegaly, and circulating IL-6. Circulating CRT positively correlates with fibrosis, splenomegaly, and soluble IL-6 in MF. Scatterplots demonstrating correlation between the plasma levels of CRT and BM fibrosis (; ), splenomegaly (; ), and circulating IL-6 (; ) in MF patients (a, b, and c, resp.) are shown. -axis of (a) shows BM fibrosis scale.

(a)

(b)

(c)