Chemokines and Chemokine Receptors in the Development of Lupus Nephritis

Table 2

Chemokine receptors and chemokines likely to mediate cell infiltration into the kidney in human LN.

Chemokine receptor	Chemokine(s)	Target cell type(s)	Reference(s)
CXCR5	CXCL13	Podocytes, B cells,	[34, 35]
CXCR4	CXCL12	B cells, CD4^+ T cells	[62–65]
CXCR3	CXCL10	CD4^+ T cells, T cells, CD19 B cells	[26, 63, 66–68]
CCR1	CCL3, 5	CD68^+ macrophages	[63, 69]
CCR5	CCL3, 4, 5	T cells	[70]
CCR2	CCL2	CD4^+ T cells, CD8^+ T cells	[63]
CX3CR1	CX3CL1	CD16^+ cells	[71]