Research Article
Association of Serum Adropin Concentrations with Diabetic Nephropathy
Table 3
Logistic regression analysis for determining the risk factor of developing DN.
| | Characteristics | Adjusting for age and gender | Simple logistic regression | Multiple logistic regression | | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P |
| | Age (years) | 1.001 (0.978–1.024) | 0.961 | 1.010 (0.989–1.031) | 0.373 | — | — | | Gender (M/F) | 1.167 (0.673–2.024) | 0.583 | 1.036 (0.626–1.715) | 0.891 | — | — | | BMI (kg/m2) | — | — | 1.029 (0.960–1.103) | 0.414 | — | — | | SBP (mmHg) | — | — | 1.024 (1.012–1.035) | <0.001 | 1.024 (1.006–1.041) | 0.008 | | DBP (mmHg) | — | — | 1.030 (1.011–1.048) | 0.001 | 1.007 (0.980–1.035) | 0.618 | | HbA1c (%) | — | — | 1.093 (0.911–1.311) | 0.340 | — | — | | TG (mmol/L) | — | — | 1.126 (0.931–1.362) | 0.221 | — | — | | TC (mmol/L) | — | — | 1.298 (1.027–1.641) | 0.029 | 1.888 (0.710–5.020) | 0.203 | | HDL-C (mmol/L) | — | — | 1.419 (0.494–4.071) | 0.515 | — | — | | LDL-C (mmol/L) | — | — | 1.339 (1.010–1.775) | 0.043 | 0.665 (0.203–2.176) | 0.500 | | BUN (nmol/L) | — | — | 1.346 (1.165–1.555) | <0.001 | 1.380 (1.111–1.714) | 0.004 | | Cr (μmol/L) | — | — | 1.016 (1.005–1.028) | 0.004 | 1.003 (0.982–1.024) | 0.802 | | GFR (mL/min/1.73 m2) | — | — | 0.991 (0.984–0.999) | 0.019 | 1.010 (0.998–1.021) | 0.095 | | Adropin (ng/mL) | 0.285 (0.180–0.452) | <0.001 | 0.288 (0.183–0.453) | <0.001 | 0.270 (0.160–0.455) | <0.001 | | MetS | — | — | 1.506 (0.865–2.621) | 0.148 | — | — |
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