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Mediators of Inflammation
Volume 2016, Article ID 6423637, 6 pages
http://dx.doi.org/10.1155/2016/6423637
Clinical Study

Plasma Periostin Levels Are Increased in Chinese Subjects with Obesity and Type 2 Diabetes and Are Positively Correlated with Glucose and Lipid Parameters

Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

Received 31 December 2015; Revised 7 April 2016; Accepted 5 May 2016

Academic Editor: Fumio Tsuji

Copyright © 2016 Yuanyuan Luo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. D. Mooradian, “Dyslipidemia in type 2 diabetes mellitus,” Nature Clinical Practice Endocrinology and Metabolism, vol. 5, no. 3, pp. 150–159, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. L. Wu and K. G. Parhofer, “Diabetic dyslipidemia,” Metabolism: Clinical and Experimental, vol. 63, no. 12, pp. 1469–1479, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. K. G. Parhofer, “Interaction between glucose and lipid metabolism: more than diabetic dyslipidemia,” Diabetes & Metabolism Journal, vol. 39, no. 5, pp. 353–362, 2015. View at Publisher · View at Google Scholar
  4. M. K. Badman, P. Pissios, A. R. Kennedy, G. Koukos, J. S. Flier, and E. Maratos-Flier, “Hepatic fibroblast growth factor 21 is regulated by PPARα and is a key mediator of hepatic lipid metabolism in ketotic states,” Cell Metabolism, vol. 5, no. 6, pp. 426–437, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. T. Reinehr and C. L. Roth, “Fetuin-A and its relation to metabolic syndrome and fatty liver disease in obese children before and after weight loss,” Journal of Clinical Endocrinology and Metabolism, vol. 93, no. 11, pp. 4479–4485, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. J. Li, Y. Chi, C. Wang et al., “Pancreatic-derived factor promotes lipogenesis in the mouse liver: role of the Forkhead box 1 signaling pathway,” Hepatology, vol. 53, no. 6, pp. 1906–1916, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. D. B. Savage, K. F. Petersen, and G. I. Shulman, “Disordered lipid metabolism and the pathogenesis of insulin resistance,” Physiological Reviews, vol. 87, no. 2, pp. 507–520, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Takeshita, R. Kikuno, K. Tezuka, and E. Amann, “Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I,” Biochemical Journal, vol. 294, no. 1, pp. 271–278, 1993. View at Publisher · View at Google Scholar · View at Scopus
  9. S. J. Conway, K. Izuhara, Y. Kudo et al., “The role of periostin in tissue remodeling across health and disease,” Cellular and Molecular Life Sciences, vol. 71, no. 7, pp. 1279–1288, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. Y. Lu, X. Liu, Y. Jiao et al., “Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα,” The Journal of Clinical Investigation, vol. 124, no. 8, pp. 3501–3513, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. J. Hirosumi, G. Tuncman, L. Chang et al., “A central role for JNK in obesity and insulin resistance,” Nature, vol. 420, no. 6913, pp. 333–336, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. R. A. Morris, B. Damon, V. Mironov et al., “Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues,” Journal of Cellular Biochemistry, vol. 101, no. 3, pp. 695–711, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Horiuchi, N. Amizuka, S. Takeshita et al., “Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor β,” Journal of Bone and Mineral Research, vol. 14, no. 7, pp. 1239–1249, 1999. View at Publisher · View at Google Scholar · View at Scopus
  14. B. Merle and P. Garnero, “The multiple facets of periostin in bone metabolism,” Osteoporosis International, vol. 23, no. 4, pp. 1199–1212, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. J. K. Reddy and M. S. Rao, “Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation,” American Journal of Physiology—Gastrointestinal and Liver Physiology, vol. 290, no. 5, pp. G852–G858, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Hiukka, M. Maranghi, N. Matikainen, and M.-R. Taskinen, “PPARα: an emerging therapeutic target in diabetic microvascular damage,” Nature Reviews Endocrinology, vol. 6, no. 8, pp. 454–463, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. S. M. Grundy, H. B. Brewer Jr., J. I. Cleeman, S. C. Smith Jr., and C. Lenfant, “Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition,” Circulation, vol. 109, no. 3, pp. 433–438, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. J. C. Cohen, J. D. Horton, and H. H. Hobbs, “Human fatty liver disease: old questions and new insights,” Science, vol. 332, no. 6037, pp. 1519–1523, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. G. A. Michelotti, M. V. Machado, and A. M. Diehl, “NAFLD, NASH and liver cancer,” Nature Reviews Gastroenterology and Hepatology, vol. 10, no. 11, pp. 656–665, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. K. M. Thakali, J. Saben, J. B. Faske et al., “Maternal pregravid obesity changes gene expression profiles toward greater inflammation and reduced insulin sensitivity in umbilical cord,” Pediatric Research, vol. 76, no. 2, pp. 202–210, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. K. Bolton, D. Segal, J. McMillan, A. Sanigorski, G. Collier, and K. Walder, “Identification of secreted proteins associated with obesity and type 2 diabetes in Psammomys obesus,” International Journal of Obesity, vol. 33, no. 10, pp. 1153–1165, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. G. S. Hotamisligil, “Inflammation and metabolic disorders,” Nature, vol. 444, no. 7121, pp. 860–867, 2006. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Y. Liu, H. Zheng, and G. Ouyang, “Periostin, a multifunctional matricellular protein in inflammatory and tumor microenvironments,” Matrix Biology, vol. 37, pp. 150–156, 2014. View at Publisher · View at Google Scholar · View at Scopus
  24. M. W. Bradbury, “Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis,” American Journal of Physiology—Gastrointestinal and Liver Physiology, vol. 290, no. 2, pp. G194–G198, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. S. Amara, K. Lopez, B. Banan et al., “Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: potential role in liver fibrosis,” Molecular Immunology, vol. 64, no. 1, pp. 26–35, 2015. View at Publisher · View at Google Scholar · View at Scopus