Dyslipidemia and Diabetes Increase the OPG/TRAIL Ratio in the Cardiovascular System

Figure 1

Effect of dyslipidemia and diabetes on atherosclerosis and cardiomyocyte hypertrophy. (a) Representative en face aortic sections showing atherosclerosis. (b) Percentage of the aorta stained red with Sudan IV in each group. Result from CNT is not shown, as there was no plaque present. (c) Representative H&E-stained hearts (original magnification 25x) and (d) related cardiomyocyte size quantification (in μm). Scale bar = 50 μm. Data show mean ± SEM. versus CNT; versus ApoE. CNT is for C57BL/6J mice; ApoE is for ApoE^−/− mice; ApoE + DM is for ApoE^−/− mice + diabetes mellitus.

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