Dyslipidemia and Diabetes Increase the OPG/TRAIL Ratio in the Cardiovascular System

Figure 2

Effect of dyslipidemia and diabetes on OPG, TRAIL gene expression, and OPG/TRAIL ratio in the aorta and the heart. (a) Aortic messenger RNA expression of OPG, TRAIL, and OPG/TRAIL ratio, reported as relative gene units. (b) Cardiac messenger RNA expression of OPG, TRAIL, and OPG/TRAIL ratio, reported as relative gene units. Data are expressed as mean ± SEM. versus CNT; versus ApoE. CNT is for C57BL/6J mice; ApoE is for ApoE^−/− mice; ApoE + DM is for ApoE^−/− mice + diabetes mellitus.

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