Elevated Expression of Programmed Death-1 and Programmed Death Ligand-1 Negatively Regulates Immune Response against Cervical Cancer Cells

Figure 6

Effect of PD-L1 on lymphocyte proliferation and the secretion of IL-10 and TGF-β. Anti-PD-L1 antibody was used to block PD-L1. (a) Lymphocyte proliferation determined using MTT assay. Concentrations of (b) IL-10 and (c) TGF-β of culture supernatants measured using CBA assay. compared with control group; compared with cervical cancer + anti PD-L1 group; compared with CIN + anti-PD-L1 group.

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