Plasma Leptin Is Elevated in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Figure 2

Plasma leptin can predict the mortality of IPF patients independently. (a) Plasma leptin was significantly elevated in decedents () than that in survivors () (). (b) Kaplan-Meier analyses showed patients with AE-IPF had a significantly higher mortality rate compared with S-IPF subjects by log-rank test (). (c) Patients with plasma leptin levels above 13.79 ng/mL had a higher mortality than those with leptin levels lower than that (). (d) The survival had no significant difference between patients with plasma KL-6 levels 500 U/mL and those ≤500 U/mL ().

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