Cytokines and Effector/Regulatory Cells Characterization in the Physiopathology of Cutaneous Lupus Erythematous: A Cross-Sectional Study

Figure 5

Circulating CD4 effector T and regulatory cells in patients with cutaneous lupus. (a) IL-22-producing CD4 T cells, (b) IL-17-secreting CD4 T cells, (c) IL-4-expressing CD4 T cells, (d) IFN-γ-producing CD4 T cells, (e) Foxp3-expressing CD4 T cells, (f) IL-10-producing B cells, and (g) IDO-expressing pDC cells. Results are expressed as mean (yellow line), median (black line), and 5th/95th percentiles. HD: healthy donor, HSc: hypertrophic scar, DLE: discoid lupus erythematosus, and SCLE: subacute cutaneous lupus erythematosus. (h) Representative flow plot. .

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