Cytokines and Effector/Regulatory Cells Characterization in the Physiopathology of Cutaneous Lupus Erythematous: A Cross-Sectional Study

Table 1

Demographic and clinical characteristics from patients with cutaneous lupus erythematosus.

	HD	HSc	DLE	SCLE	value
Demographics
Age (years)
Median	45	29	39	35
Range	(21–76)	(24–33)	(18–74)	(20–62)	0.003
Sex (female %)	100	100	95	93	NS
Disease duration (years)
Median	—	—	7	6	NS
Range			(1–26)	(1–41)
Laboratory variables
Leukocytes (cells/mL)
Median	5500	ND	5200	6100	NS
Range	(4200–8200)		(2400–6700)	(2200–15700)
Lymphocytes (%)
Median	29	ND	20	19	0.028
Range	(18–47)		(14–33)	(8–33)
ESR (mmHg)
Median	6	1	8	10	0.0024
Range	(2–18)	(1–15)	(2–28)	(2–48)
Anti-dsDNA (IU/mL)
Median			16	45
Range	—	—	(8–111)	(12–447)	<0.001
C3 (mg/dL)
Median			79	79
Range	—	—	(24–134)	(29–130)	NS
C4 (mg/dL)
Median	—	—	14	14	NS
Range			(8–29)	(6–37)
Clinical variables
CLASI activity score
Median			11	21
Range	—	—	(2–25)	(9–37)	<0.001
Prednisone (mg/day)
Median			5	10
Range	—	—	(0–30)	(0–50)	0.0037
Antimalarial (%)	—	—	75	67	0.043

HD: healthy donors; HSc: hypertrophic scar; DLE: discoid lupus erythematosus; SCLE: subacute cutaneous lupus erythematosus.