The Th17/Treg Immune Imbalance in Ulcerative Colitis Disease in a Chinese Han Population

Figure 3

Flow cytometric analysis of the percentage of Th17 and Treg cells in peripheral blood. (a) Percentage of Th17 in peripheral blood in healthy control subjects. (b) Percentage of Th17 in peripheral blood in mild type subgroup of UC patients. (c) Percentage of Th17 in peripheral blood in moderate and severe type subgroup of UC patients. (d) Percentage of Treg cells in peripheral blood in healthy control subjects. (e) Percentage of Treg cells in peripheral blood in mild type subgroup of UC patients. (f) Percentage of Treg cells in peripheral blood in moderate and severe type subgroup of UC patients. In (a), (b), and (c), in the quadrant 1 (Q1), the IL-17A PE-A antibody is positive; the CD4 APC-A antibody is negative; in Q2, both the IL-17A PE-A and CD4 APC-A antibody are positive; in Q3, both the IL-17A PE-A and CD4 APC-A antibody are negative; in Q4, the IL-17A PE-A antibody is negative; the CD4 APC-A antibody is negative. In (d), (e), and (f), in Q1, the foxP3 PE-A antibody is positive; the CD4 FITC-A antibody is negative; in Q2, both the foxP3 PE-A and CD4 FITC-A antibody are positive; in Q3, both the foxP3 PE-A and CD4 FITC-A antibody are negative; in Q4, the foxP3 PE-A antibody is negative; the CD4 FITC-A antibody is negative.

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