[Retracted] Neuropilin-1^highCD4⁺CD25⁺ Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis

Figure 2

Sepsis markedly upregulated the expression of Foxp-3/CTLA-4/TGF- on Tregs. Midgrade septic model at 24 hours after CLP was used to investigate the effect of Nrp-1 on the negative immunoregulation of Tregs in sepsis. The expressions of Nrp-1 and Foxp-3 ((a), (c)) and CTLA-4 and TGF- ((b), (c)) were subjected to flow cytometric analysis by flow cytometer. Data was represented as mean ± standard deviation (SD) and analyzed by SPSS 17.0 software with a one-way ANOVA, per group ().

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