Serum Amyloid A Promotes E-Selectin Expression via Toll-Like Receptor 2 in Human Aortic Endothelial Cells

<div>Effect of TLR2 siRNA on the expression of TLR and selectin cascade genes in HAECs. The mRNA expression levels of TLR2, MYD88, NFKB1, TNF-<i>α</i>, and SELE were examined in HAECs treated with TLR2 siRNA (closed column). After SAA stimulation for 0, 1, 3, and 6 h, the mRNA expression of all genes was dramatically decreased compared with the control (open column). Data represent the mean ± SD of four independent experiments. 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Mediators of Inflammation

fig5

Figure 5

Figure 5: Serum Amyloid A Promotes E-Selectin Expression via Toll-Like Receptor 2 in Human Aortic Endothelial Cells 