Anti-Inflammatory Effect of Rhapontici Radix Ethanol Extract via Inhibition of NF-κB and MAPK and Induction of HO-1 in Macrophages

Figure 5

Effects of RRE treatment on the phosphorylation of (a) ERK, (b) p38, and (c) JNK MAPKs in RAW 264.7 cells. Cells were treated with RRE for 1 h and challenged with LPS for 30 min. ERK, p38, and JNK, as well as their phosphorylated forms (p-ERK, p-p38, and p-JNK), were examined by Western blot. Results are representative of three independent experiments.