Activation of Melanocortin Receptors MC₁ and MC₅ Attenuates Retinal Damage in Experimental Diabetic Retinopathy

Figure 1

Representative images of FAG performed at baseline and after 8, 12, and 16 weeks from diabetes induction. There were no alterations worthy of note at 8 weeks. At 12 weeks from diabetic induction there was an increase in vascular tortuosity with some microvascular changes such as microaneurysms that were also evident after 16 weeks of diabetes. Each group consisted of 10 mice in which 8 developed clear signs of retinopathy. Ma = microaneurysms.