Research Article
Kidney Expression of Toll Like Receptors in Lupus Nephritis: Quantification and Clinicopathological Correlations
Table 2
TLR3, TLR7, TLR8, and TLR9 expressions in kidney section of lupus nephritis patients and healthy controls.
| | | | Lupus nephritis () | Controls () | | | | | Median (IQR) | Median (IQR) |
| | TLR3 | W | 1071 (1170) | 360 (309) | 0.026 | | G | 667 (476) | 234 (211) | ns | | TI | 485 (524) | 127 (903) | 0.031 |
| | TLR7 | W | 1718 (1962) | 903 (1278) | ns | | G | 983 (1409) | 231 (741) | ns | | TI | 932 (677) | 314 (480) | 0.022 |
| | TLR8 | W | 321 (875) | 623 (888) | ns | | G | 189 (602) | 358 (516) | ns | | TI | 109 (248) | 164 (193) | ns |
| | TLR9 | W | 667 (1119) | 41 (65) | <0.001 | | G | 372 (646) | 14 (41) | 0.003 | | TI | 237 (282) | 27 (25) | 0.007 |
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W, whole kidney expression; G, glomerular expression; TI, tubulointerstitial expression.
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