Table 3: Number of positive cells/mm2 expressing each TLR at glomerular level and at tubulointerstitial level or at both in class II, class III, and class IV lupus nephritis.

Class IIClass IIIClass IV
Median (IQR)Median (IQR)Median (IQR)

TLR3W234 (354)378 (550)1492 (1414)ns
G272 (183)187 (661)480 (881)Class III versus class II: 0.03
Class III versus class IV: 0.03
TI224 (72)168 (159)702 (574)ns

TLR7W1617 (332)3396 (1656)2531 (1612)ns
G1075 (1174)1996 (1656)1414 (892)ns
TI1168 (1192)1381 (1162)1127 (778)ns

TLR8W155 (31)202 (247)300 (123)ns
G55 (22)132 (164)200 (215)ns
T100 (52)72 (52)107 (99)ns

TLR9W234 (354)378 (550)1492 (1414)ns
G272 (183)187 (661)480 (881)Class IV versus class II: 0.05
Class IV versus class III: 0.01
TI224 (72)168 (159)702 (574)Cass IV versus class II: 0.02
Class IV versus class III: 0.04

W, whole kidney expression; G, glomerular expression; TI, tubulointerstitial expression.