Research Article

Elevated Admission Base Deficit Is Associated with a Complex Dynamic Network of Systemic Inflammation Which Drives Clinical Trajectories in Blunt Trauma Patients

Table 1

Overall demographics, clinical outcomes, mechanism of injury, blood and blood components, comorbidities, and disposition of the BD < 4 () and BD 4 () subgroups. Values are expressed as mean ± SEM. Mann–Whitney U test, Fisher exact test, or Chi-square were used as appropriate with statistical significance set at .

BD < 4BD ≥ 4 value

Demographics
Age, yr45.76 ± 20.34
Sex, male/femaleM = 55 F = 15M = 55 F = 290.07
Injury severity score (ISS)21 ± 1.323 ± 1.20.15
Glasgow coma scale (GCS)12.7 ± 0.5212.6 ± 0.560.46
Outcome
Intensive Care Unit length of stay, days6.6 ± 0.799.9 ± 0.960.005
Hospital length of stay, days11.9 ± 0.9717.4 ± 1.2<0.001
Mechanical ventilation, days3 ± 0.565.5 ± 0.870.02
Mechanism of Injury
Motor vehicle crashes (MVC), n (%)47 (67%)55 (65%)0.98
Fall, n (%)8 (11.5%)10 (12%)
Motorcycle, n (%)8 (11.5%)9 (11%)
Others, n (%)7 (10%)10 (12%)
Blood and Blood Components
24 h packed RBC, n (%)10 (14.3%)27 (32.2%)0.001
24 h blood components (platelets, FFP, and cryoprecipitate), n (%)4 (5.7%)0 (0%)
24 h PRBC + other components (platelets, FFP, and cryoprecipitate), n (%)6 (8.6%)16 (19%)
None, n (%)50 (71.4%)41 (48.8%)
Comorbid Conditions
Hypertension, n (%)22 (31.4%)20 (23.8%)0.3
Diabetes mellitus, n (%)10 (14.3%)9 (10.7%)0.5
Smoking, n (%)4 (5.7%)6 (7.2%)0.7
Cardiovascular, n (%)10 (14.3%)12 (14.3%)1
Pulmonary, n (%)3 (4.3%)8 (9.5%)0.2
Endocrine, n (%)15 (21.4%)8 (9.5%)0.04
Gastrointestinal, n (%)6 (8.6%)5 (6%)0.5
Peripheral vascular disease, n (%)2 (2.9%)0 (0%)0.12
Neurological, n (%)8 (11.4%)4 (4.8%)0.12
Psychiatric, n (%)6 (8.6%)9 (10.7%)0.65
Drug and Alcohol Abuse, n (%)4 (5.7%)4 (4.8%)0.79
Renal, n (%)0 (0%)4 (4.8%)0.06
Rheumatologic, n (%)0 (0%)4 (4.8%)0.06
Hematologic, n (%)3 (4.3%)1 (1.2%)0.23
Previous admission for trauma, n (%)01 (1.2%)0.36
None, n (%)22 (31.4%)32 (38.1%)0.39
Disposition
Home, n (%)34 (48.6%)23 (27.4%)0.005
Home with service, n (%)2 (2.9%)1 (1.2%)
Inpatient rehabilitation facility, n (%)6 (8.6%)1 (1.2%)
Outpatient rehabilitation facility, n (%)11 (15.7%)17 (20.2%)
Skilled nursing facility, n (%)16 (22.9%)39 (46.4%)
Others, n (%)1 (1.4%)3 (3.6%)