Elevated Admission Base Deficit Is Associated with a Complex Dynamic Network of Systemic Inflammation Which Drives Clinical Trajectories in Blunt Trauma Patients

Table 2

Summary of the area under the curve (AUC) analysis in the first 24 h after injury for statistically significantly different inflammatory mediators (by two-way ANOVA) between the BD < 4 and BD 4 subgroups.

Inflammation biomarkers (0–24 h after injury)	BD ≥ 4 (pg.h/L)	BD < 4 (pg.h/L)	Fold change	value
IL-1RA	2268.0	728.3	3.1	<0.001
IL-7	208.0	94.6	2.2	0.036
IL-8/CCL8	222.3	103.7	2.1	0.004
sIL-2Rα	711.2	373.8	1.9	0.005
MCP-1/CCL2	2336.7	1423.3	1.6	0.048