Caffeoylquinic Acid Derivatives Extract of Erigeron multiradiatus Alleviated Acute Myocardial Ischemia Reperfusion Injury in Rats through Inhibiting NF-KappaB and JNK Activations
Effects of AE on myocardial infarct size after I/R in rats. (a) Representative TTC stained left ventricle slices are shown. Deep red-staining areas indicate normal tissue and unstained pale areas indicate infarct tissue. (b) Experimental protocol. Hearts were subjected to 30 min ischemia followed by 24-hour reperfusion. Different doses of AE (10, 20, or 40 mg/kg), CAPE 5 mg/kg, or saline (1 mL/kg) were administered via the tail vein 1 min before reperfusion. (c) Myocardial infarct size determined by TTC staining. /group. , versus Sham; versus I/R vehicle.
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