Maternal Vitamin D Level Is Associated with Viral Toll-Like Receptor Triggered IL-10 Response but Not the Risk of Infectious Diseases in Infancy
Table 3
Association of maternal and cord serum 25(OH)D levels with clinical outcome at 1 year of age.
Univariate
p
Multivariate
p
OR (95% CI)
OR (95% CI)
Maternal serum 25(OH)D
Bronchiolitis
1.26 (0.47, 3.37)
0.65
1.25 (0.42, 3.71)
0.69
Pneumonia
2.57 (0.41, 16.07)
0.31
4.58 (0.52, 40.51)
0.17
Croup
7.10 (0.85, 60.81)
0.07
13.29 (0.88, 199.8)
0.06
Enteritis
1.20 (0.36, 4.02)
0.77
1.47 (0.38, 5.62)
0.58
UTI
0.85 (0.25, 2.94)
0.80
0.92 (0.26, 3.24)
0.92
Cord serum 25(OH)D
Bronchiolitis
2.22 (0.90, 5.47)
0.08
1.13 (0.42, 3.04)
0.81
Pneumonia
1.70 (0.36, 7.94)
0.51
2.38 (0.22, 25.46)
0.47
Croup
3.82 (0.67, 21.81)
0.13
4.64 (0.75, 28.80)
0.10
Enteritis
0.98 (0.36, 2.69)
0.97
1.42 (0.43, 4.69)
0.56
UTI
0.75 (0.25, 2.29)
0.62
0.78 (0.25, 2.45)
0.67
Total number of children aged 1 year: 321. Number of bronchiolitis: 45 (14%), pneumonia: 11 (3.4%), croup: 8 (2.5%), infectious enteritis: 22 (6.9%), and UTI (urinary tract infection): 27 (8.4%). Adjusted for gestational age, sex, birth body weight, mode of delivery, season of birth, and maternal allergy.
