Interleukin-22 Might Act as a Double-Edged Sword in Type 2 Diabetes and Coronary Artery Disease
Table 1
Clinical characteristics of Batch 2 patients.
Clinical parameters
Control (n = 110)
T2DM (n = 58)
CAD (n = 132)
T2DM-CAD (n = 137)
Age, years
58.15 ± 9.84
61.16 ± 14.38
65.67 ± 9.93
65.69 ± 9.82
Men, n (%)
54 (49.1)
35 (60.3)
79 (59.8)
67 (48.9)
BMI (kg/m2)
24.66 (22.86, 25.38)
23.86 (22.26, 26.99)
24.33 (22.6, 25.36)
24.72 (22.97, 26.12)
Hypertension, n (%)
62 (56.4)
30 (51.7)
92 (69.7)
103 (75.2)
Stroke, n (%)
13 (11.8)
13 (22.4)
32 (24.2)
48 (35)
Smoke, n (%)
34 (30.9)
10 (17.2)
51 (38.6)
46 (33.6)&
Alcohol consumption, n (%)
13 (11.8)
5 (8.6)
26 (19.7)
16 (11.7)
FBS (mmol/L)
5.2 (4.91, 5.53)
6.39 (7.65, 11.07)
5.36 (4.88, 5.84)
7.83 (6.53, 10.32)
HbA1c (%)
4.9 (4.78, 5.2)
6.4 (5.55, 8.25)
5.1 (4.7, 5.5)
6.5 (5.6, 7.8)
TC (mmol/L)
4.48 ± 0.3
4.56 ± 1.11
4.54 ± 1.02
4.56 ± 1.26
TG (mmol/L)
1.11 (0.77, 1.76)
1.39 (0.84, 1.89)
1.29 (0.91, 1.86)
1.42 (1.11, 2.26)
HDL (mmol/L)
1.25 ± 0.31
1.11 ± 0.37
1.21 ± 0.33
1.09 ± 0.32
LDL (mmol/L)
2.54 ± 0.77
2.48 ± 0.92
2.62 ± 0.76
2.57 ± 1.01
Urea (mmol/L)
5.38 (4.65, 6.43)
6.07 (4.76, 7.26)
5.58 (4.54, 6.85)
6.19 (5.02, 7.83)
Creatinine (mmol/L)
66.2 (55.9, 80.35)
74.3 (61.1, 90.2)
77.65 (63.68, 93.63)
75 (58.05, 88.05)
BMI, body mass index; CAD, coronary artery disease; FBS, fasting blood sugar; HbA1c, hemoglobin A1C; HDL, high-density lipoprotein; LDL, low-density lipoprotein; T2DM, type 2 diabetes mellitus; TC, total cholesterol; TG, triglycerides. Data are presented as mean ± standard deviation or median (25th percentile; 75th percentile). Alcohol consumption refers to an average ethanol consumption up to 15 g/day for women and 30 g/day for men. , , and versus control group. and versus T2DM group. and versus CAD group.
