Interleukin-22 Might Act as a Double-Edged Sword in Type 2 Diabetes and Coronary Artery Disease

Table 2

Logistic regression analysis for the incidence of T2DM, CAD, and T2DM-CAD.

Clinical parameters	⁢Simple regression		⁢Multiple regression
	OR (95% CI)		OR (95% CI)
IL-22 (pg/mL)	1.042 (1.023, 1.062)	0.000015	1.027 (1.004, 1.050)	0.022
Age (per/yr)	1.062 (1.039, 1.086)	0.000000	1.082 (1.048, 1.111)	0.000002
Sex (male)	1.295 (0.840, 1.996)	0.243
BMI (kg/m^2)	0.991 (0.920, 1.067)	0.811
Hypertension (yes)	1.750 (1.122, 2.728)	0.014	0.916 (0.418, 2.009)	0.827
Stroke (yes)	2.978 (1.591, 5.574)	0.001	0.940 (0.338, 2.614)	0.905
Smoking (yes)	0.937 (0.587, 1.494)	0.783
Drinking (yes)	1.121 (0.613, 2.051)	0.712
TC (per mmol/L)	1.062 (0.851, 1.326)	0.595
TG (per mmol/L)	1.210 (0.946, 1.548)	0.129
HDL (per mmol/L)	0.381 (0.183, 0.790)	0.01	0.433 (0.152, 1,227)	0.115
LDL (per mmol/L)	1.043 (0.789, 1.379)	0.766
FBS (per mmol/L)	1.690 (1.372, 2.082)	0.000001	1.637 (1.316, 2.035)	0.000009
HbA1c (%)	3.505 (2.243, 5.478)	0.000000	1.388 (0.636, 3.031)	0.411
Urea (per mmol/L)	1.198 (1.058, 1.355)	0.004	0.905 (0.747, 1.096)	0.307
Creatinine (per mmol/L)	1.018 (1.007, 1.028)	0.001	1.007 (0.988, 1.026)	0.411