Acanthopanax versus 3-Methyladenine Ameliorates Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting the Autophagic Pathway in Rats

Figure 1

Pathological changes of the pancreas by light microscopy and pathological scores of pancreatic tissues. (a) SAP group at 3 h; (b) SAP group at 24 h; (c) SO group at 24 h; (d) Aca group at 24 h; (e) 3-MA group at 24 h (HE, ×200). (f) Comparison of pancreas pathological scores; versus SO group at the same time point; ; versus SAP group at the same time point; 12 h versus 3 h in the same group, ; 24 h versus 12 h in the same group, ; ; 24 h versus 3 h in the same group, . SO: sham operation; SAP: SAP model; Aca: Acanthopanax; 3-MA: 3-methyladenine.

(a) SAP group at 3 h

(b) SAP group at 24 h

(c) SO group at 24 h

(d) Aca group at 24 h

(e) 3-MA group at 24 h

(f)