Semisynthesis of Derivatives of Oleanolic Acid from Syzygium aromaticum and Their Antinociceptive and Anti-Inflammatory Properties

<div>Semisynthetic pathways: (i) (CH3CO2)2O, pyridine, 12 hrs, 25°C, (ii) CH3I, DMF, 12 hrs, 25°C, (iii) K2CO3, CH3I, 12 hrs, 25°C, and (v) (CF3CO2C)2O, pyridine, 12 hrs, 0°C.</div>

Mediators of Inflammation

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Figure 1

Figure 1: Semisynthesis of Derivatives of Oleanolic Acid from Syzygium aromaticum and Their Antinociceptive and Anti-Inflammatory Properties