Novel Role of Endogenous Catalase in Macrophage Polarization in Adipose Tissue

Figure 2

Catalase deficiency favors M1 activation and inflammation in the stromal vascular fraction of epididymal WAT. (a) To measure M1 activation, CD11c (1 : 200) was assessed by immunohistochemistry (brown) and quantified in Image Pro. Scale bar, 50 μm; magnification, 200x. Samples were costained with hematoxylin (blue). (b) CD11c, (c) TNF-α, and (d) PAI-1 mRNA levels were determined by real-time PCR. Data are mean ± SE of 6–8 mice. .

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