The Impact of Obstructive Sleep Apnoea and Nasal Continuous Positive Airway Pressure on Circulating Ischaemia-Modified Albumin Concentrations
Table 1
Demographic, clinical characteristics and laboratory values of the study group.
Group 1 Control group ()
Group 2 Mild OSAS ()
Group 3 Moderate OSAS ()
Group 4 Severe OSAS ()
Age (year)
49.2 ± 13.1
53 ± 7.8
51.7 ± 11.5
52.6 ± 9.8
0.570
Male/female gender
21/9
23/9
19/12
27/7
0.456
BMI (kg/m2)
28.9 ± 4.4
29.4 ± 4.5
30.1 ± 3.5
31.4 ± 4.7
0.091
Smoker/nonsmoker
14/16
12/20
14/17
14/20
0.884
Comorbidities
Hypertension
7
8
11
17
0.095
Diabetes mellitus
3
3
5
7
0.518
Hyperlipidemia
6
9
8
10
0.839
Polysomnographic study results
Total sleep time (TST), h
6.7 ± 1.3
6.2 ± 1.1
6.4 ± 1.2
6.1 ± 0.9
0.620
Sleep efficiency (%)
84.7 ± 10.3
84.7 ± 9.5
83.8 ± 10.6
84 ± 9.8
0.974
Stages 3, % of TST
21.4 ± 6.4
15.4 ± 10
12.9 ± 7.9
9.2 ± 4.8
<0.001
REM, % of TST
23.7 ± 4.1
18.3 ± 5.9
15.8 ± 5.2
11.8 ± 5.6
<0.001
AHI, h
1.8 ± 1.3
8.6 ± 2.1
18.8 ± 5
50 ± 18.8
<0.001
Mean oxygen saturation, %
93.2 ± 3
88.8 ± 3.5
83.5 ± 4.7
73 ± 9.2
<0.001
Desaturation index
4.16 ± 4.2
14.3 ± 8
26.4 ± 26.6
59.7 ± 25.7
<0.001
ESS
4.7 ± 2.3
8.8 ± 3
11.2 ± 3.5
15.8 ± 3.8
<0.001
IMA (ABSU)
0.415 ± 0.068
0.457 ± 0.077
0.516 ± 0.089
0.577 ± 0.063
<0.001
CRP (mg/L)
1.56 ± 1.2
2 ± 1
3.1 ± 1.4
4.4 ± 1.8
<0.001
OSAS: obstructive sleep apnea syndrome, BMI: body mass index, REM: rapid eye movement, AHI: apnea-hypopnea index, ESS: Epworth Sleepiness Scale, IMA: ischaemia-modified albumin, and CRP: C-reactive protein. Data are presented as means ± 1 standard deviation. Statistically significantly different from groups 2, 3, and 4. Statistically significantly different from groups 3 and 4. Statistically significantly different from group 4.
