Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Accelerates the Progression of Renal Fibrosis in Lupus Nephritis by Activating SMAD and p38 MAPK in TGF-<i>β</i>1 Signaling Pathway

<div>Distribution of TWEAK and Fn14 in kidneys of MRL/Lpr mice. Immunohistochemistry staining of kidneys shows strong expression of TWEAK and Fn14 in the kidneys from MRL/lpr mice, but they were only weakly seen in the kidney of MRL/MPJ mice. Control: MRL/lpr mice treated with PBS and MRL/MPJ: MRL/MPJ mice as normal control. Scale bar: 50 <i>μ</i>m.</div>

Mediators of Inflammation

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Figure 3: Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Accelerates the Progression of Renal Fibrosis in Lupus Nephritis by Activating SMAD and p38 MAPK in TGF-<i>β</i>1 Signaling Pathway 

Figure 3 | Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Accelerates the Progression of Renal Fibrosis in Lupus Nephritis by Activating SMAD and p38 MAPK in TGF-β1 Signaling Pathway 