Intraplaque Expression of C-Reactive Protein Predicts Cardiovascular Events in Patients with Severe Atherosclerotic Carotid Artery Stenosis
Table 5
Relationship between serum hs-CRP and intraplaque parameters.
Upstream
Downstream
hs-CRP, μg/mL vs.
value
hs-CRP, μg/mL vs.
value
Neutrophils/mm2
0.045
0.547
Neutrophils/mm2
0.107
0.147
Total collagen, %
−0.108
0.150
Total collagen, %
−0.017
0.819
Collagen I, %
−0.118
0.116
Collagen I, %
0.103
0.167
Collagen III, %
−0.038
0.614
Collagen III, %
0.064
0.393
CRP, %
−0.088
0.268
CRP, %
−0.013
0.871
Smooth muscle cells, %
−0.053
0.482
Smooth muscle cells, %
−0.031
0.673
Total macrophages (CD68+)†, %
0.016
0.832
Total macrophages (CD68+)†, %
0.056
0.451
M‡1 subset (CD86+), %
0.038
0.630
M‡1 subset (CD86+), %
−0.101
0.207
M1 subset (HLA-DR+), %
−0.098
0.222
M1 subset (HLA-DR+), %
−0.034
0.671
M2 subset (CD163+), %
0.055
0.481
M2 subset (CD163+), %
−0.055
0.485
Correlations were performed by Spearman’s rank correlation coefficient. CRP: high sensitivity c-reactive protein. †CD: cluster of differentiation. ‡M: macrophage. HLA-DR: human leukocyte antigen-antigen D related.
