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Mediators of Inflammation
Volume 2016 (2016), Article ID 9340637, 5 pages
http://dx.doi.org/10.1155/2016/9340637
Review Article

Therapeutic Effects of Quercetin on Inflammation, Obesity, and Type 2 Diabetes

1College of Bioscience and Biotechnology, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
2Hunan Province University Key Laboratory for Agricultural Biochemistry and Biotransformation, Hunan Agricultural University, Changsha 410128, China
3Hunan CoInnovation Center for Ultilization of Botanical Functional Ingredients, Changsha 410128, China

Received 16 August 2016; Accepted 20 November 2016

Academic Editor: Michael Conlon

Copyright © 2016 Shuang Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

In previous studies, abdominal obesity has been related to total low-grade inflammation and in some cases has resulted in insulin resistance and other metabolism related disorders such as diabetes. Quercetin is a polyphenol, which is a derivative of plants, and has been shown in vitro as well as in a few animal models to have several potential anti-inflammatory as well as anticarcinogenic applications. The substance has also been shown to aid in the attenuation of lipid peroxidation, platelet aggregation, and capillary permeability. However, further research is called for to gain a better understanding of how quercetin is able to provide these beneficial effects. This manuscript reviewed quercetin’s anti-inflammatory properties in relation to obesity and type 2 diabetes.