Epigenetic Modulation as a Therapeutic Prospect for Treatment of Autoimmune Rheumatic Diseases

Table 1

FDA-approved epigenetic drugs.

Drug	Epigenetic effect	Clinical trial
Miravirsen	Neutralisation of miRNA-122	Phase II [13]
MRX34	Ectopic expression of miRNA-34	Phase I [9]
Azacitidine (Vidaza)	DNA methyltransferase inhibitor	Phase III [15]
Decitabine (Dacogen)	DNA methyltransferase inhibitor	Phase III [17]
Vorinostat (Zolinza)	Pan-HDAC inhibitor	Phase II [24]