Effect of Interleukin-15 on CD11b, CD54, and CD62L Expression on Natural Killer Cell and Natural Killer T-Like Cells in Systemic Lupus Erythematosus

Figure 1

The CD11b, CD54, and CD62L expression on (a) CD56⁺CD3⁻ NK cells, (b) CD56⁻CD3⁺ T cells, and (c) CD56⁺CD3⁺ NKT-like cells from SLE patients and healthy controls. PBMCs were stimulated with IL-15 (10 ng/mL) for 18 hrs. Cells were stained by anti-CD3 and anti-CD56 antibodies and segregated into CD56⁺CD3⁻ NK cells, CD56⁻CD3⁺ T cells, and CD56⁺CD3⁺ NKT-like cells. Surface marker (CD11b, CD54, or CD62L) expression on each cell population was analyzed by flow cytometry. Data was expressed as percent expression (%) ± SEM. compared to normal; compared to medium (normal, ; SLE, ).

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