Effect of Interleukin-15 on CD11b, CD54, and CD62L Expression on Natural Killer Cell and Natural Killer T-Like Cells in Systemic Lupus Erythematosus

Figure 4

The inhibition of CD62L expression by IL-15 on CD56⁺CD3⁻ NK cells and CD56⁺CD3⁺ NKT-like cells from SLE and healthy donors. PBMCs were stained with anti-CD3, anti-CD56, and anti-CD62L antibodies and were analyzed under flow cytometry. % CD62L downregulation by IL-15 is calculated as [MFI of CD62L in medium − MFI of CD62L in the presence of IL-15 (10 ng/mL) for 18 hours/MFI of CD62L in medium] × 100. (normal, ; SLE, ).