Table of Contents Author Guidelines Submit a Manuscript
Mediators of Inflammation
Volume 2016, Article ID 9797021, 10 pages
http://dx.doi.org/10.1155/2016/9797021
Research Article

Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis

1Department of Pharmacology, Medical School, Université de Sherbrooke, 3001 12th Avenue North, Sherbrooke, QC, Canada J1H 5N4
2Department of Pediatrics, Program of Immunology and Allergology, Medical School, Université de Sherbrooke, 3001 12th Avenue North, Sherbrooke, QC, Canada J1H 5N4
3Department of Medical Biochemistry and Microbiology, Uppsala University BMC, Box 582, 75123 Uppsala, Sweden
4Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, P.O. Box 7070, 75007 Uppsala, Sweden

Received 20 March 2016; Revised 13 June 2016; Accepted 21 July 2016

Academic Editor: Sandra Helena Penha Oliveira

Copyright © 2016 Louisane Desbiens et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The mMCP-4 KO mice have been backcrossed for over 10 generations with C57BL/6 congeners and are highly congenial with the later strain (E. Tchougounova, G. Pejler and M. Abrink, The Journal of experimental medecine, vol. 198, no. 3, pp. 423-431, 2003) [ref. n°25]. The genotype of mMCP-4 KO mice used in the present study was confirmed by polymerase chain reaction (PCR) (as shown in supplementary Figure 1) via the use of primers described in Supplemental Table 1.

  1. Supplementary Material