Involvement of Toll Like Receptor 2 Signaling in Secondary Injury during Experimental Diffuse Axonal Injury in Rats

Figure 1

Pathological changes after DAI in rat cortex. (a) Pathological changes in rat cortex of DAI 3 d and control groups were confirmed by H&E staining, β-APP immunohistochemistry (scale bar = 100 μm), and silver stain (scale bar = 20 μm). (b) The bar graphs showed the statistical results for β-APP expression in the cortex ( = 6; < 0.05, compared with control group). The relative increase in β-APP levels was calculated in 10 random fields (40x magnification) and assessed by densitometry (IOD). Data were presented as mean ± SD in three separate experiments.

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