Involvement of Toll Like Receptor 2 Signaling in Secondary Injury during Experimental Diffuse Axonal Injury in Rats

Figure 5

Identification of optimal concentration of Pam3CSK4. (a) The optimal doses of Pam3CSK4 (0.5, 1, or 2 mg/kg) were determined by western blotting of β-APP. β-Actin was used as an internal control. (b) The bar graphs showed the statistical results for β-APP expression. Values were presented as mean ± SD (n = 6; < 0.05, compared with control group; < 0.05, compared with DAI 3 d + vehicle group; < 0.05, compared with DAI 3 d + Pam3CSK4 (0.5 mg/kg); > 0.05, compared with DAI 3 d + Pam3CSK4 (1 mg/kg)).

(a)

(b)