Visfatin Triggers Anorexia and Body Weight Loss through Regulating the Inflammatory Response in the Hypothalamic Microglia
The effect of visfatin on the microglia inflammation. The BV2 cells were set up at 2 × 105 cell/well and treated with visfatin at indicated concentration for 24 h. (a–d). The levels of MCP-1, TNF-α, IL-6, and IL-1β were detected by ELISA ( for each group). ND: no significant difference. (e–h) The levels of MCP-1, TNF-α, IL-6, and IL-1β mRNA were detected by qRT-PCR ( for each group). Results are presented as mean ± SEM. , , and .