Visfatin Triggers Anorexia and Body Weight Loss through Regulating the Inflammatory Response in the Hypothalamic Microglia
Visfatin induces changes in the number of microglial cells and the intensity of Iba-1 protein signals in the hypothalamus. (a) Representative images showing immunostaining of Iba-1 in the hypothalamic arcuate nucleus. Scale bar = 100 μm. (b) Number of microglial cells and (c) intensity of Iba-1 signals observed in the hypothalamic areas (ARC, VMH, and DMH) and hippocampal CA1 (HIPPO) of mice following icv injection of visfatin compared to those in vehicle-injected mice. for control (CTL) and for visfatin. Results are presented as mean ± SEM. ,, and .
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