MCL Plays an Anti-Inflammatory Role in <i>Mycobacterium tuberculosis</i>-Induced Immune Response by Inhibiting NF-<i>κ</i>B and NLRP3 Inflammasome Activation

<div>Illustration of the mechanism underlying the inhibitory effect of MCL on Mtb-induced immunopathologic response. MCL can suppress the phosphorylation of Akt causing the subsequently inhibitory effect on NF-<i>κ</i>B and NLRP3 inflammasome, which then impair the production of proinflammatory cytokines and finally alleviate tuberculosis immunopathology.</div>

Mediators of Inflammation

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Figure 8

Figure 8: MCL Plays an Anti-Inflammatory Role in <i>Mycobacterium tuberculosis</i>-Induced Immune Response by Inhibiting NF-<i>κ</i>B and NLRP3 Inflammasome Activation 

Figure 8 | MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation 