The Clinical Significance of Increased Serum Proinflammatory Cytokines, C-Reactive Protein, and Erythrocyte Sedimentation Rate in Patients with Hidradenitis Suppurativa

Table 1

Demographics of healthy controls and patients with hidradenitis suppurativa.

	Healthy controls	Patients with hidradenitis suppurativa
n	22 (10 males, 12 females)	74 (36 males, 38 females)
Age (years), mean ± SD	37.4 ± 13.4	37.4 ± 12.0
Smoking, current smoker, n (%)	0 (0%)	57 (77)
BMI, kg/m^2
Normal weight: BMI ≤ 24.9, n (%)	Normal weight: 20 (91.0)	Normal weight: 18 (24.3)
Overweight: BMI ≥ 25, n (%)	Overweight: 2 (9.1)	Overweight: 24 (32.4)
Obesity: BMI ≥ 30, n (%)		Obesity: 32 (43.2)
HS-PGA, mean ± SD		3.0 ± 0.9
Clinical inflammatory activity
LIA: HS-PGA ≤ 2, n (%)		LIA: 22 (29.7)
MIA: HS-PGA = 3, n (%)		MIA: 35 (47.3)
HIA: HS-PGA ≥ 4, n (%)		HIA: 17 (23.0)
Hurley staging system		Stage I: 11 (14.9)
		Stage II: 47 (63.5)
		Stage III: 16 (21.6)

BMI: body mass index; HS-PGA: Hidradenitis Suppurativa-Physician Global Assessment; LIA: low inflammatory activity; MIA: moderate inflammatory activity; HIA: high inflammatory activity. There were no significant differences in age and male/female ratio between the patients with hidradenitis suppurativa and healthy controls ().