Statins Reduce Lipopolysaccharide-Induced Cytokine and Inflammatory Mediator Release in an In Vitro Model of Microglial-Like Cells

Table 1

Chemical structure and properties of the commonly prescribed statins [7].

Statin	Molecular structure	Lipophilicity	Half-life
Atorvastatin		Lipophilic	14 h
Fluvastatin		Lipophilic	2.3 h
Pitavastatin		Lipophilic	12 h
Pravastatin		Hydrophilic	2.7 h
Rosuvastatin		Hydrophilic	19 h
Simvastatin		Lipophilic	3 h