Stigmasterol Modulates Allergic Airway Inflammation in Guinea Pig Model of Ovalbumin-Induced Asthma

Figure 1

Effect of stigmasterol on inflammatory cell count in blood. Guinea pigs were sensitized and challenged with ovalbumin as described in the methods. Animals received either saline, dexamethasone, or stigmasterol 1 h prior to each challenge. Naïve controls received normal saline only. Animals were sacrificed 24 h after the last challenge, and blood was collected for counts of eosinophil (a), lymphocyte (b), and monocyte (c). Data is expressed as cell count (10³/μL) ± SEM (). , , and as compared to saline-treated control; ^### and ^## as compared to naïve control using one-way ANOVA followed by Dunnet’s post hoc test.

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