Resistin as a Prooxidant Factor and Predictor of Endothelium Damage in Patients with Mild Acute Pancreatitis Exposed to Tobacco Smoke Xenobiotics
Table 3
Cotinine, Cd, IL-6, AAT, and AGP concentrations in the blood of healthy subjects and patients with AP in the 1st, 3rd, and 7th day of hospitalization.
Parameters
Control group
Patients with AP
Nonsmokers Median (range)
Smokers Median (range)
Nonsmokers Median (range)
Smokers Median (range)
Cotinine (ng/ml)
1st day
0.98 (0.02–14.51)
72.62(1) (24.48–215.97)
0.75 (0.11–2.53)
130.22(2), (3) (71.37–245.11)
3rd day
0.35 (0.09–1.24)
97.69(2) (2.16–246.48)
7th day
0.22 (0.05–0.91)
104.93(2), (4) (0.20–174.68)
Cd (μg/l)
1st day
0.12 (0.0–0.48)
0.91(1) (0.22–1.37)
0.79(1) (0.14–2.69)
4.17(2), (3) (0.83–12.48)
3rd day
0.91 (0.38–4.97)
4.20(2) (0.95–19.37)
7th day
1.09 (0.31–2.83)
3.74(2) (0.31–8.83)
IL-6 (pg/ml)
1st day
0.26 (0.10–14.63)
0.44(1) (0.10–98.40)
3.20(1) (2.09–31.93)
2.02(3) (1.52–102.06)
3rd day
4.05 (2.59–24.47)
2.45 (1.29–75.62)
7th day
4.05 (2.48–6.93)
3.62 (1.32–106.58)
AAT (g/l)
1st day
1.69 (1.09–2.16)
1.86 (0.72–3.31)
2.60(1) (1.08–4.39)
2.04 (0.62–3.79)
3rd day
2.05 (1.13–3.05)
2.36 (1.01–5.02)
7th day
4.57(4), (5) (2.17–7.75)
3.74(4), (5) (2.83–7.63)
AGP (g/l)
1st day
1.20 (0.85–1.52)
1.31 (0.79–1.87)
2.22(1) (1.20–4.76)
2.93(3) (1.92–4.16)
3rd day
2.94 (1.92–4.31)
2.82 (1.72–5.17)
7th day
3.53 (1.14–7.15)
4.65(4), (5) (2.23–8.87)
(1) compared to nonsmokers of control group. (2) compared to nonsmoking patients with AP. (3) compared to smokers of control group. (4) compared to the 1st day of hospitalization. (5) compared to the 3rd day of hospitalization.
