Inhibition of Murine Pulmonary Microvascular Endothelial Cell Apoptosis Promotes Recovery of Barrier Function under Septic Conditions

Figure 7

Inhibition of caspase activity reduces PMVEC apoptosis. (a) Stimulation of PMVEC with cytomix (24 h) led to a significant increase in TUNEL+ cells and this increase was significantly reduced by treatment with Q-VD (50 μM). . (b) Flow cytometric analysis revealed an increased number of early apoptotic PMVEC (Annexin V+/PI−) following cytomix stimulation (16 h) that was significantly reduced by treatment with Q-VD (50 μM). . or ## represents compared with vehicle or cytomix group, respectively (one-way ANOVA).

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