Clinical Study

Short-Term Postoperative Cognitive Dysfunction and Inflammatory Response in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Pilot Study

Table 4

OR estimates for serum levels of inflammatory markers and S-100β on POCD from logistic regression analyses.

UnadjustedAdjusted by age and FBS
OR95% CIOR95% CI

Maximum IL-1β concentrationa1.26(1.09, 1.55)1.41(1.08, 1.85)
Maximum HMGB-1 concentrationa1.09(0.94, 1.46)1.02(0.91, 1.38)
Maximum SAA concentrationa1.01(0.81, 1.29)0.98(0.75, 1.24)
Maximum S-100β concentrationb1.15(1.07, 1.44)1.25(1.09, 1.63)

OR: odds ratio; CI: confidence interval; FBS: fasting blood sugar; IL-1β: interleukin 1β; HMGB-1: high mobility group box-1 protein; SAA: serum amyloid A; S-100β: S100 calcium-binding protein B. ORs for a24 h postoperatively, ORs for b1 h postoperatively.