Research Article

Tabetri™ (Tabebuia avellanedae Ethanol Extract) Ameliorates Osteoarthritis Symptoms Induced by Monoiodoacetate through Its Anti-Inflammatory and Chondroprotective Activities

Figure 2

Ta-EE reduced the serum levels of inflammatory mediators and proinflammatory cytokines in MIA-induced OA rats. MIA-induced OA rats were orally administered with either Ta-EE (30–120 mg/kg), MSM (155 mg/kg), or Pc-LE (20 mg/kg) once a day, and the levels of (a) PGE2, (b) LTB4, (c) IL-1β, and (d) IL-6 in the sera of the rats in each group were measured at weeks zero, two, and four. , versus a control group; # and ## versus a normal group; and week 0 versus week 2 or 4; and week 2 versus week 4.
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