FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines

Figure 1

The concentration of S1P in serum and urine was positively correlated with chronic kidney disease renal injury. Forty IgA nephropathy patients and 10 healthy volunteers were selected. The 24 h urine and plasma were collected. Concentrations of S1P in plasma and urine were measured by using ELISA. (a) Concentrations of S1P in plasma in IgA nephropathy patients and healthy volunteers. (b) Concentrations of S1P in 24 h urine in IgA nephropathy patients and healthy volunteers. (c) Concentrations of S1P in plasma in IgA nephropathy patients with different level of proteinuria and healthy volunteers. (d) Concentrations of S1P in 24 h urine from IgA nephropathy patients with different level of proteinuria and healthy volunteers. Data were expressed as means ± standard error of the mean from the independent sample in the same group. , versus normal group in (a) and (b). , versus heavy group or low-level group in (c) and (d).

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