Research Article

High Levels of Hemoglobin Promote Carotid Adventitial Vasa Vasorum Neoangiogenesis in Chronic Kidney Disease

Table 2

Carotid IMT and carotid adventitial VV values in control subjects and patients affected by chronic kidney disease.

Control ()CKD 3-4 ()CKD 5D ()LRT (C versus CKD 3-4) (C versus 5D) (CKD 3-4 versus 5D)

ARight cIMT0.63 ± 0.110.71 ± 0.150.78 ± 0.14<0.001 (0.006)0.005 (0.248)<0.001 (0.002)0.028 (0.043)
Left cIMT0.66 ± 0.130.72 ± 0.150.79 ± 0.16<0.001 (0.055)0.030<0.0010.053

BRight VV0.59 0.69 0.62 0.011 (0.022)0.003 (0.007)0.227 (0.295)0.147 (0.147)
Left VV0.56 0.58 0.53 0.606 (0.487)

Identified variables with normal distribution. Descriptive values are expressed as mean ± SD or median [IQR] depending on their normal distribution according to Shapiro-Wilks test. Adjusted values in multiple comparisons are not performed for variables with nonsignificant differences according to the overall test ( overall). The column “LRT ” refers to the likelihood ratio test value measuring the overall differences among groups by comparing the models with and without group identification. Box-Cox transformation of the dependent variable to get normally distributed residuals from the multivariate linear regression analysis. Age adjusted value in linear regression analysis.