Mediators of Inflammation

Research Article

High Levels of Hemoglobin Promote Carotid Adventitial Vasa Vasorum Neoangiogenesis in Chronic Kidney Disease

Table 3

Association between adventitial VV and biochemical and anthropometric variables in CKD patients.


	CKD 3-4				CKD 5D
	Right VV		Left VV		Right VV		Left VV
	Correlation	value	Correlation	value	Correlation	value	Correlation	value

Age (years)	0.0666	0.6913	−0.1730	0.3279	−0.0788	0.6790	0.2077	0.2708
WC (cm)	0.1106	0.5084	−0.0870	0.6245	−0.0627	0.7466	−0.1939	0.3064
BMI (Kg/m²)	0.1226	0.4635	−0.0212	0.9051	0.2107	0.2636	−0.1618	0.3931
Glucose (mg/dL)	0.2134	0.2183	−0.2012	0.2777	0.4691	0.0089	0.0726	0.7029
Cholesterol (mg/dL)	0.0507	0.7722	0.1797	0.3335	0.3547	0.0545	−0.2098	0.2658
HDL cholesterol (mg/dL)	−0.2872	0.0943	−0.1220	0.5133	0.5044	0.0073	0.1116	0.5871
LDL cholesterol (mg/dL)	0.1696	0.3301	0.0217	0.9076	0.2486	0.2111	−0.1562	0.4461
TG (mg/dL)	0.1711	0.3259	0.3021	0.0986	0.0974	0.6088	−0.1953	0.3009
SBP (mmHg)	0.0165	0.9215	−0.3020	0.0826	−0.1072	0.5945	−0.1881	0.3378
DBP (mmHg)	−0.1329	0.4262	−0.2240	0.2029	−0.0542	0.7885	−0.3296	0.0868
CRP (mg/L)	0.2230	0.3169	0.1123	0.6471	−0.0024	0.9898	0.0265	0.8898
Ca (mg/dL)	0.0117	0.9468	0.0306	0.8702	0.0031	0.9869	−0.4805	0.0072
P (mg/dL)	−0.0686	0.6943	−0.0157	0.9331	−0.2310	0.2193	−0.1963	0.2986
PTH (pg/mL)	−0.3066	0.1649	−0.1738	0.4768	−0.1056	0.6000	−0.2124	0.2767
25D (ng/mL)	0.0902	0.6175	0.0874	0.6519	0.1395	0.4621	0.1600	0.3984
1,25D (pg/mL)	0.0089	0.9656	0.1404	0.5439	−0.2132	0.2667	0.0175	0.9311
Albumin (mg/dL)	−0.0547	0.7586	0.0710	0.7092	0.1052	0.5802	0.3785	0.0392
Ferritin (mg/dL)	0.0378	0.8680	−0.2115	0.3847	−0.2234	0.2354	−0.0476	0.8096
Hemoglobin (g/dL)	0.0572	0.7518	−0.0715	0.7123	−0.3118	0.0935	0.0661	0.7286
Fibrinogen (g/L)	0.3145	0.0966	−0.0017	0.9934	0.0913	0.6439	0.1483	0.4515
Leukocytes (10⁶/L)	0.2373	0.1835	−0.2228	0.2454	0.1861	0.3429	0.0889	0.6658
VEGF (pg/mL)	0.0645	0.7037	−0.3152	0.0740	0.2779	0.1370	0.2934	0.1224

Identified variables with normal distribution (Pearson’s correlation). For variables with significant deviations from normal distribution, Spearman’s correlation was applied. Statistically significant values are indicated in bold. WC: waist circumference; BMI: body mass index; TG: triglycerides; SBP: systolic blood pressure; DBP: diastolic blood pressure; CRP: C-reactive protein; Ca: serum calcium; P: serum phosphorus; PTH: parathyroid hormone; 25D: 25-hydroxyvitamin D; 1,25D: 1α,25-dihydroxyvitamin D; VEGF: Vascular Endothelial Growth Factor.