Research Article

High Levels of Hemoglobin Promote Carotid Adventitial Vasa Vasorum Neoangiogenesis in Chronic Kidney Disease

Table 5

Clinical and biochemical differences between nondialysis and dialysis CKD patients.

CKD 3-4 ()CKD 5D () overall

Diabetes
 No35 (79.5%)30 (81.1%)1.000
 Yes9 (20.5%)7 (18.9%)
Hypertension
 No5 (11.4%)7 (18.9%)0.522
 Yes39 (88.6%)30 (81.1%)
Dyslipidemia
 No11 (25.0%)14 (37.8%)0.315
 Yes33 (75.0%)23 (62.2%)
Etiology
 Diabetes4 (9.09%)4 (10.8%)0.296
 Glomerular6 (13.6%)12 (32.4%)
 Interstitial9 (20.5%)9 (24.3%)
 Polycystic7 (15.9%)4 (10.8%)
 Vascular8 (18.2%)3 (8.11%)
 Unknown10 (22.7%)5 (13.5%)
Plaques
 No21 (47.7%)13 (35.1%)0.359
 Yes23 (52.3%)24 (64.9%)
Right plaques
 No25 (56.8%)17 (45.9%)0.452
 Yes19 (43.2%)20 (54.1%)
Left plaques
 No27 (61.4%)21 (56.8%)0.847
 Yes17 (38.6 %)16 (43.2%)
Smoking
 Nonsmoker15 (50%)23 (62.2%)0.517
 Former smoker7 (23.3%)8 (21.6%)
 Smoker8 (26.7%)6 (16.2%)
Patients on ESA treatment
 No42 (95.5%)5 (14.7%)<0.001
 Yes2 (4.5%)29 (85.3%)
 NESP dose (µg/kg/week)0.64 0.33 0.198
Patients on iron treatment
 No39 (88.6%)17 (51.5%)0.001
 Yes5 (11.4%)16 (48.5%)
 Dose (g/month)105 102
Ca (mg/dL)9.22 ± 0.418.84 ± 0.560.001
P (mg/dL)3.62 4.16 <0.001
PTH (pg/mL)8.80 29.7 <0.001
1,25D (pg/mL)38.5 5.90 <0.001
Albumin (mg/dL)4.46 ± 0.324.25 ± 0.320.006
Ferritin (mg/dL)156 293 0.001
Hemoglobin (g/dL)13.8 ± 1.7912.4 ± 1.15<0.001
Fibrinogen (g/L)4.25 4.40 0.232
Leukocytes (106/L)6.29 5.77 0.056
REGICORE4.00 2.50 0.283
Score1.00 1.00 0.374

Identified variables with normal distribution. Values of these variables are described with mean ± standard deviation. For variables with significant deviations from normal distribution, values are provided as median [IQR]. Statistically significant values are indicated in bold. NESP: darbepoetin; Ca: serum calcium; P: serum phosphorus; PTH: parathyroid hormone; 1,25D: 1α,25-dihydroxyvitamin D; REGICORE: REgistre GIroní del COR (cardiovascular risk chart).