High Levels of Hemoglobin Promote Carotid Adventitial Vasa Vasorum Neoangiogenesis in Chronic Kidney Disease
Table 5
Clinical and biochemical differences between nondialysis and dialysis CKD patients.
CKD 3-4 ()
CKD 5D ()
overall
Diabetes
No
35 (79.5%)
30 (81.1%)
1.000
Yes
9 (20.5%)
7 (18.9%)
Hypertension
No
5 (11.4%)
7 (18.9%)
0.522
Yes
39 (88.6%)
30 (81.1%)
Dyslipidemia
No
11 (25.0%)
14 (37.8%)
0.315
Yes
33 (75.0%)
23 (62.2%)
Etiology
Diabetes
4 (9.09%)
4 (10.8%)
0.296
Glomerular
6 (13.6%)
12 (32.4%)
Interstitial
9 (20.5%)
9 (24.3%)
Polycystic
7 (15.9%)
4 (10.8%)
Vascular
8 (18.2%)
3 (8.11%)
Unknown
10 (22.7%)
5 (13.5%)
Plaques
No
21 (47.7%)
13 (35.1%)
0.359
Yes
23 (52.3%)
24 (64.9%)
Right plaques
No
25 (56.8%)
17 (45.9%)
0.452
Yes
19 (43.2%)
20 (54.1%)
Left plaques
No
27 (61.4%)
21 (56.8%)
0.847
Yes
17 (38.6 %)
16 (43.2%)
Smoking
Nonsmoker
15 (50%)
23 (62.2%)
0.517
Former smoker
7 (23.3%)
8 (21.6%)
Smoker
8 (26.7%)
6 (16.2%)
Patients on ESA treatment
No
42 (95.5%)
5 (14.7%)
<0.001
Yes
2 (4.5%)
29 (85.3%)
NESP dose (µg/kg/week)
0.64
0.33
0.198
Patients on iron treatment
No
39 (88.6%)
17 (51.5%)
0.001
Yes
5 (11.4%)
16 (48.5%)
Dose (g/month)
105
102
Ca (mg/dL)
9.22 ± 0.41
8.84 ± 0.56
0.001
P (mg/dL)
3.62
4.16
<0.001
PTH (pg/mL)
8.80
29.7
<0.001
1,25D (pg/mL)
38.5
5.90
<0.001
Albumin (mg/dL)
4.46 ± 0.32
4.25 ± 0.32
0.006
Ferritin (mg/dL)
156
293
0.001
Hemoglobin (g/dL)
13.8 ± 1.79
12.4 ± 1.15
<0.001
Fibrinogen (g/L)
4.25
4.40
0.232
Leukocytes (106/L)
6.29
5.77
0.056
REGICORE
4.00
2.50
0.283
Score
1.00
1.00
0.374
Identified variables with normal distribution. Values of these variables are described with mean ± standard deviation. For variables with significant deviations from normal distribution, values are provided as median [IQR]. Statistically significant values are indicated in bold. NESP: darbepoetin; Ca: serum calcium; P: serum phosphorus; PTH: parathyroid hormone; 1,25D: 1α,25-dihydroxyvitamin D; REGICORE: REgistre GIroní del COR (cardiovascular risk chart).